Eighty Known Effectors Aligned to H. glycines Genome V1


Eighty effectors have been previously identified in H. glycines (1-2). The mRNA sequences of these effectors were aligned to the H. glycines genome V1 to identify their genomic sources.  Many of the functions of these effectors have been characterized, some of include: defense suppression, alterations of plant hormone signaling, epigenetic modification, metabolic manipulation, and cytoskeletal modifications (reviewed by 3-6).

Gene lists of effector names vs genomic gene names:  effectors2genetable.rtf

Functional gene annotations and locations in gff format:   121effectoronlynewgenenamesgenegff.rtf


1) Gao B, Allen R, Maier T, Davis EL, Baum TJ, Hussey RS: The parasitome of the phytonematode Heterodera glycines. Molecular Plant-Microbe Interactions 2003, 16(8):720-726.

2) Noon JB, Hewezi TAF, Maier TR, Simmons C, Wei J-Z, Wu G, Llaca V, Deschamps S, Davis E, Mitchum M: Eighteen new candidate effectors of the phytonematode Heterodera glycines produced specifically in the secretory esophageal gland cells during parasitism. Phytopathology 2015(ja).

3) Hewezi T, Baum TJ: Manipulation of plant cells by cyst and root-knot nematode effectors. Molecular Plant-Microbe Interactions 2013, 26(1):9-16.

4) Hewezi T: Cellular signaling pathways and posttranslational modifications mediated by nematode effector proteins. Plant physiology 2015, 169(2):1018-1026.

5) Juvale PS, Baum TJ: “Cyst-ained” research into Heterodera parasitism. PLoS pathogens 2018, 14(2):e1006791.

6) Mitchum MG, Hussey RS, Baum TJ, Wang X, Elling AA, Wubben M, Davis EL: Nematode effector proteins: an emerging paradigm of parasitism. New Phytologist 2013, 199(4):879-894.